Protection mediated by chemokine CXCL10 in BALB/c mice infected by Leishmania infantum

Protection mediated by chemokine CXCL10 in BALB/c mice infected by Leishmania infantum

BACKGROUND Visceral leishmaniasis (VL) caused by Leishmania infantum is characterised by the loss of the ability of the host to generate an effective immune response. Chemokines have a direct involvement in the pathogenesis of leishmaniasis, causing a rapid change in the expression of these molecul...

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Bibliographic Details
Main Authors: Webertty Mayk Eufrásio Figueiredo, Sayonara de Melo Viana, Dorotheia Teixeira Alves, Priscila Valera Guerra, Zirlane Castelo Branco Coêlho, Helene Santos Barbosa, Maria Jania Teixeira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
L. infantum
CXCL10
mice
nitric oxide
cytokines
macrophages
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000800561&lng=en&tlng=en

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