Hyperthermia-induced NDRG2 upregulation inhibits the invasion of human hepatocellular carcinoma via suppressing ERK1/2 signaling pathway.

Hyperthermia (HT) has been proven to be able to alter the invasion capacity of cancer cells. However, the detailed mechanisms responsible for the anti-metastasis effects of HT have not been elucidated. N-myc downstream-regulated gene 2 (NDRG2), as a member of the NDRG family, has been suggested to b...

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Bibliographic Details
Main Authors: Yan Guo, Ji Ma, Lin Wu, Qianrong Wang, Xia Li, Xiaoming Li, Yuan Zhang, Jian Zhang, Libo Yao, Jing Zhang, Wenchao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3632536?pdf=render