Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream with Janus kinases (JAK) family protein and capable of integrating inputs from different signaling pathways. Each family member plays unique functions in signal transduction and crucial in mediating cellular respon...

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Bibliographic Details
Main Authors: Chin-Yap Loh, Aditya Arya, Ahmed Fadhil Naema, Won Fen Wong, Gautam Sethi, Chung Yeng Looi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Oncology
Subjects:
STAT transcription factors
cancer
inflammation
therapeutic implication
STAT3
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00048/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00048/full

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