Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

Anorectal malformations (ARMs) are relatively common congenital abnormalities, but their pathogenesis is poorly understood. Previous gene knockout studies indicated that the signalling pathway mediated by the retinoic acid receptors (RAR) is instrumental to the formation of the anorectal canal and o...

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Bibliographic Details
Main Authors: Manuel Mark, Marius Teletin, Olivia Wendling, Jean-Luc Vonesch, Betty Féret, Yann Hérault, Norbert B. Ghyselinck
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
mouse embryonic development
congenital malformations
vitamin A deficiency
Fraser syndrome
umbilical artery
mesenteric artery
Online Access:https://www.mdpi.com/2227-9059/9/7/742

Internet

https://www.mdpi.com/2227-9059/9/7/742

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