Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

Abstract Background We have proved fecal microbiota transplantation (FMT) is an efficacious remedy to mitigate acute radiation syndrome (ARS); however, the mechanisms remain incompletely characterized. Here, we aimed to tease apart the gut microbiota-produced metabolites, underpin the therapeutic ef...

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Bibliographic Details
Main Authors: Hui-wen Xiao, Ming Cui, Yuan Li, Jia-li Dong, Shu-qin Zhang, Chang-chun Zhu, Mian Jiang, Tong Zhu, Bin Wang, Hai-Chao Wang, Sai-jun Fan
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Microbiome
Subjects:
Radiotherapy
Acute radiation syndrome
Gastrointestinal tract toxicity
Hematopoietic toxicity
Gut microbiota
Gut microbiota metabolite
Online Access:http://link.springer.com/article/10.1186/s40168-020-00845-6

Internet

http://link.springer.com/article/10.1186/s40168-020-00845-6

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