Home Sweet Home: The Tumour Microenvironment as a Haven for Regulatory T Cells

Home Sweet Home: The Tumour Microenvironment as a Haven for Regulatory T Cells

CD4+Foxp3+ regulatory T cells (Tregs) have a fundamental role in maintaining immune balance by preventing autoreactivity and immune-mediated pathology. However this role of Tregs extends to suppression of anti-tumour immune responses and remains a major obstacle in the development of anti-cancer vac...

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Bibliographic Details
Main Authors: Beatrice Omusiro Ondondo, Awen eGallimore, Emma eJones, Andrew eGodkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Chemokines
regulatory T cells
tumour immunology
immunotherapy of cancer
intra-tumoural proliferation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00197/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00197/full

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