Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.

Recent studies indicate that extracellular vesicles are an important source material for many clinical applications, including minimally-invasive disease diagnosis. However, challenges for rapid and simple extracellular vesicle collection have hindered their application. We have developed and valida...

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Bibliographic Details
Main Authors: Anirban Ghosh, Michelle Davey, Ian C Chute, Steven G Griffiths, Scott Lewis, Simi Chacko, David Barnett, Nicolas Crapoulet, Sébastien Fournier, Andrew Joy, Michelle C Caissie, Amanda D Ferguson, Melissa Daigle, M Vicki Meli, Stephen M Lewis, Rodney J Ouellette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4201556?pdf=render