Structural and Functional Characterization of the FadR Regulatory Protein from Vibrio alginolyticus

Structural and Functional Characterization of the FadR Regulatory Protein from Vibrio alginolyticus

The structure of Vibrio cholerae FadR (VcFadR) complexed with the ligand oleoyl-CoA suggests an additional ligand-binding site. However, the fatty acid metabolism and its regulation is poorly addressed in Vibrio alginolyticus, a species closely-related to V. cholerae. Here, we show crystal structure...

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Bibliographic Details
Main Authors: Rongsui Gao, Defeng Li, Yuan Lin, Jingxia Lin, Xiaoyun Xia, Hui Wang, Lijun Bi, Jun Zhu, Bachar Hassan, Shihua Wang, Youjun Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
FadR
ligand
fatty acid sensing
virulence
Vibrio alginolyticus
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00513/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00513/full

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