Sequential Delivery of Dual Growth Factors from Injectable Chitosan-Based Composite Hydrogels

Local administration of platelet-derived growth factor-BB (PGDF-BB) and bone morphogenetic protein-2 (BMP-2) in a sequential release manner could substantially promote bone healing. To achieve this goal, a delivery system that could sustain the release of PGDF-BB and BMP-2 by way of temporal separat...

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Bibliographic Details
Main Authors: Qing Min, Jiaoyan Liu, Xiaofeng Yu, Yuchen Zhang, Jiliang Wu, Ying Wan
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/17/6/365