Brain tight junction protein expression in sepsis in an autopsy series

Abstract Background Neuroinflammation often develops in sepsis along with increasing permeability of the blood-brain barrier (BBB), which leads to septic encephalopathy. The barrier is formed by tight junction structures between the cerebral endothelial cells. We investigated the expression of tight...

Full description

Bibliographic Details
Main Authors: Kristo Erikson, Hannu Tuominen, Merja Vakkala, Janne Henrik Liisanantti, Tuomo Karttunen, Hannu Syrjälä, Tero Ilmari Ala-Kokko
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-020-03101-3