Scaffold Proteins Regulating Extracellular Regulated Kinase Function In Cardiac Hypertrophy and Disease

Scaffold Proteins Regulating Extracellular Regulated Kinase Function In Cardiac Hypertrophy and Disease

The mitogen activated protein kinase (MAPK)-extracellular regulated kinase 1/2 (ERK1/2) pathway is a central downstream signaling pathway that is activated in cardiac muscle cells during mechanical and agonist-mediated hypertrophy. Studies in genetic mouse models deficient in ERK-associated MAPK com...

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Bibliographic Details
Main Authors: Yan eLiang, Farah eSheikh
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pharmacology
Subjects:
mouse models
cardiac hypertrophy
cardiac myocyte
MAPK and ERK signalling
scaffolding proteins
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00037/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00037/full

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