Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

Abstract Background A fundamental fact in biology states that genes do not operate in isolation, and yet, methods that infer regulatory networks for single cell gene expression data have been slow to emerge. With single cell sequencing methods now becoming accessible, general network inference algor...

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Bibliographic Details
Main Authors: Shuonan Chen, Jessica C. Mar
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2217-z