Synthesis and antimycobacterial evaluation of new gem- difluorohydrazides

Synthesis and antimycobacterial evaluation of new gem- difluorohydrazides

<div class="WordSection1"><p><em>Several gem-difluorohydrazides were prepared by the addition of nitrogen nucleophiles to N-acetyl-2,2-gem-difluoroxindoles substituted in position 5. Initially, commercial isatin was N-acetylated using acetic anhydride. The subsequent step...

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Bibliographic Details
Main Authors: Frederico S. C. Branco, Evanoel Crizanto de Lima, Núbia Boechat, Angelo C. Pinto, Maria Cristina S. Lourenço
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2012-06-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
tuberculosis
isoniazid
difluorhydrazides
Online Access:http://orbital.ufms.br/index.php/Chemistry/article/view/346

Internet

http://orbital.ufms.br/index.php/Chemistry/article/view/346

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