Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency
Abstract Understanding the functional impact of genomic variants is a major goal of modern genetics and personalized medicine. Although many synonymous and non-coding variants act through altering the efficiency of pre-mRNA splicing, it is difficult to predict how these variants impact pre-mRNA spli...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-06-01
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| Series: | Genome Biology |
| Online Access: | http://link.springer.com/article/10.1186/s13059-018-1437-x |