Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis.

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis.

Interferon protects mice from vesicular stomatitis virus (VSV) infection and pathogenesis; however, it is not known which of the numerous interferon-stimulated genes (ISG) mediate the antiviral effect. A prominent family of ISGs is the interferon-induced with tetratricopeptide repeats (Ifit) genes c...

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Bibliographic Details
Main Authors: Volker Fensterl, Jaime L Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A Stohlman, Cornelia C Bergmann, Michael S Diamond, Herbert W Virgin, Ganes C Sen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3355090?pdf=render

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http://europepmc.org/articles/PMC3355090?pdf=render

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