Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats

Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats

BackgroundNicotine is the major addictive component of cigarette smoke and the prime culprit of the failure to quit smoking. Common elements perpetuating the use of addictive drugs are (i) cues associated with the setting in which drug was used and (ii) relapse/reinstatement mediated by an increased...

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Bibliographic Details
Main Authors: María Elena Quintanilla, Paola Morales, Fernando Ezquer, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
acetylsalicylic acid
N-acetylcysteine
nicotine
oxidative stress
reinstatement
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2020.617418/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2020.617418/full

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