Ezrin/Exocyst Complex Regulates Mucin 5AC Secretion Induced by Neutrophil Elastase in Human Airway Epithelial Cells

Ezrin/Exocyst Complex Regulates Mucin 5AC Secretion Induced by Neutrophil Elastase in Human Airway Epithelial Cells

Background/Aim: Increased mucin secretion is a characteristic feature of many chronic airway diseases, particularly during periods of exacerbation; however, the exact mechanism of mucin secretion remains unclear. Ezrin, which is a specific marker of apical membranes, is predominantly concentrated in...

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Bibliographic Details
Main Authors: Qi Li, Na Li, Chun-Yi Liu, Rui Xu, Victor P. Kolosov, Juliy M. Perelman, Xiang-Dong Zhou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ezrin
Sec3
Mucin 5AC
Neutrophil elastase
Phosphatidylinositol 4,5-bisphosphate
Online Access:http://www.karger.com/Article/FullText/369699

Internet

http://www.karger.com/Article/FullText/369699

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