Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

Abstract The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor 1 receptor (CSF1R) axis has gained the most atten...

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Bibliographic Details
Main Authors: Michael A. Cannarile, Martin Weisser, Wolfgang Jacob, Anna-Maria Jegg, Carola H. Ries, Dominik Rüttinger
Format: Article
Language:English
Published: BMJ Publishing Group 2017-07-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
CSF1
CSF1R
Tumor-associated macrophage
Clinical trial
Cancer therapy
PVNS
Online Access:http://link.springer.com/article/10.1186/s40425-017-0257-y

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http://link.springer.com/article/10.1186/s40425-017-0257-y

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