Dendritic spine density is increased on nucleus accumbens D2 neurons after chronic social defeat

Abstract Stress alters the structure and function of brain reward circuitry and is an important risk factor for developing depression. In the nucleus accumbens (NAc), structural and physiological plasticity of medium spiny neurons (MSNs) have been linked to increased stress-related and depression-li...

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Bibliographic Details
Main Authors: Megan E. Fox, Antonio Figueiredo, Miriam S. Menken, Mary Kay Lobo
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-69339-7