Downregulation of the Hsp90 system causes defects in muscle cells of Caenorhabditis elegans.

The ATP-dependent molecular chaperone Hsp90 is required for the activation of a variety of client proteins involved in various cellular processes. Despite the abundance of known client proteins, functions of Hsp90 in the organismal context are not fully explored. In Caenorhabditis elegans, Hsp90 (DA...

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Bibliographic Details
Main Authors: Andreas M Gaiser, Christoph J O Kaiser, Veronika Haslbeck, Klaus Richter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182237?pdf=render