Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection

Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection

Tissue microenvironment functions as an important determinant of the inflammatory response elicited by the resident cells. Yet, the underlying molecular mechanisms remain obscure. Our systems-level analyses identified a duration code that instructs stimulus specific crosstalk between TLR4-activated...

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Bibliographic Details
Main Authors: Balaji Banoth, Budhaditya Chatterjee, Bharath Vijayaragavan, MVR Prasad, Payel Roy, Soumen Basak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
inflammation
innate immunity
lymphotoxin
Citrobacter rodentium
positive feedback
RelA:p52/NF-kappaB
Online Access:https://elifesciences.org/articles/05648

Internet

https://elifesciences.org/articles/05648

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