Illuminating spatial and temporal organization of protein interaction networks by mass spectrometry-based proteomics

Protein-protein interactions are at the core of all cellular functions and dynamic alterations in protein interactions regulate cellular signaling. In the last decade, mass spectrometry-based proteomics has delivered unprecedented insights into human protein interaction networks. Affinity purificati...

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Bibliographic Details
Main Authors: Jiwen eYang, Sebastian Alexander Wagner, Petra eBeli
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00344/full