Protein-Mediated and RNA-Based Origins of Replication of Extrachromosomal Mycobacterial Prophages
Bacteriophages are the most abundant biological entities in the biosphere and are a source of uncharacterized biological mechanisms and genetic tools. Here, we identify segments of phage genomes that are used for stable extrachromosomal replication in the prophage state. Autonomous replication of so...
Main Authors: | Katherine S. Wetzel, Haley G. Aull, Kira M. Zack, Rebecca A. Garlena, Graham F. Hatfull |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-03-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.00385-20 |
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