Bistability in glycolysis pathway as a physiological switch in energy metabolism.

The flux of glycolysis is tightly controlled by feed-back and feed-forward allosteric regulations to maintain the body's glucose homeostasis and to respond to cell's growth and energetic needs. Using a mathematical model based on reported mechanisms for the allosteric regulations of the en...

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Bibliographic Details
Main Authors: Bhanu Chandra Mulukutla, Andrew Yongky, Prodromos Daoutidis, Wei-Shou Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24911170/?tool=EBI