Comprehensive study of altered proteomic landscape in proximal renal tubular epithelial cells in response to calcium oxalate monohydrate crystals

Abstract Background Calcium oxalate monohydrate (COM), the major crystalline composition of most kidney stones, induces inflammatory infiltration and injures in renal tubular cells. However, the mechanism of COM-induced toxic effects in renal tubular cells remain ambiguous. The present study aimed t...

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Bibliographic Details
Main Authors: Zhu Wang, Ming-xing Li, Chang-zhi Xu, Ying Zhang, Qiong Deng, Rui Sun, Qi-yi Hu, Sheng-ping Zhang, Jian-wen Zhang, Hui Liang
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Urology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12894-020-00709-z