The Hypoxic Microenvironment Induces Stearoyl-CoA Desaturase-1 Overexpression and Lipidomic Profile Changes in Clear Cell Renal Cell Carcinoma

The Hypoxic Microenvironment Induces Stearoyl-CoA Desaturase-1 Overexpression and Lipidomic Profile Changes in Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cell carcinoma (RCC). It is characterized by a high cell proliferation and the ability to store lipids. Previous studies have demonstrated the overexpression of enzymes associated with lipid metabolism, includin...

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Bibliographic Details
Main Authors: Juan Pablo Melana, Francesco Mignolli, Tania Stoyanoff, María V. Aguirre, María A. Balboa, Jesús Balsinde, Juan Pablo Rodríguez
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
kidney
hypoxia
tumor microenvironment
SCD-1
oleic acid
Online Access:https://www.mdpi.com/2072-6694/13/12/2962

Internet

https://www.mdpi.com/2072-6694/13/12/2962

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