MiR-10b Directly Targets ZEB1 and PIK3CA to Curb Adenomyotic Epithelial Cell Invasiveness via Upregulation of E-Cadherin and Inhibition of Akt Phosphorylation

Background/Aims: Adenomyosis is a disease in which ectopic endometrial glands and stromal cells appear in the uterine myometrium. Despite its prevalence, the molecular mechanisms involved in the development of adenomyosis are largely unknown. The aim of this study was to investigate the role of miR-...

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Bibliographic Details
Main Authors: Ying Guo, Xiao Lang, Zhen Lu, Jianchao Wang, Ting Li, Ying Liao, Chunyan Jia, Wenxia Zhao, Huiqi Fang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Akt
Online Access:http://www.karger.com/Article/FullText/374022