Comparison of the anti-cancer effect of Disulfiram and 5-Aza-CdR on pancreatic cancer cell line PANC-1

Comparison of the anti-cancer effect of Disulfiram and 5-Aza-CdR on pancreatic cancer cell line PANC-1

Background: Pancreatic cancer has poor prognosis by surgical and chemotherapy when it is diagnosed, so other anti-cancerous assistant therapeutic drugs are suggested e.g. epigenetic reversal of tumor-suppressor genes on promoter hypermethylation. 5-Aza-CdR is a nucleoside analog of DNMTi but it has...

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Bibliographic Details
Main Authors: Mehdi Nikbakht Dastjerdi, Zahra Babazadeh, Mansour Salehi, Batool Hashemibeni, Mohammad Kazemi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
5-Aza-CdR; Disulfiram; DNMT inhibitor; epigenetic; p21; PANC-1; RASSF1A
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=156;epage=156;aulast=Dastjerdi

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=156;epage=156;aulast=Dastjerdi

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