Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice

ABSTRACT. Purpose. Bilobalide is an active constituent of Ginkgo biloba and has shown neuroprotective effects in mice with cerebral ischemia. In the present study, we investigated brain permeability of bilobalide (i) in healthy mice and (ii) in mice before or after stroke. Methods. We have used in v...

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Bibliographic Details
Main Authors: Dorothee Lang, Christian Ude, Mario Wurglics, Manfred Schubert-Zsilavecz, Jochen Klein
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2010-12-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/9452