The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles

The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles

Intracranial electroencephalography (EEG) is commonly used to study epileptogenesis and epilepsy in experimental models. Chronic gliosis and neurodegeneration at the injury site are known to be associated with surgically implanted electrodes in both humans and experimental models. Currently, however...

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Bibliographic Details
Main Authors: Karen Tse, Edward Beamer, Deborah Simpson, Robert J. Beynon, Graeme J. Sills, Thimmasettappa Thippeswamy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
intracerebral electrodes
traumatic brain injury
neuroinflammation
proinflammatory cytokines
epilepsy
blood-brain barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.625017/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.625017/full

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