IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells.

Human mesenchymal stem cells (hMSCs) are currently investigated for a variety of therapeutic applications. However, MSCs isolated from primary tissue cannot meet clinical grade needs and should be expanded in vitro for several passages. Although hMSCs show low possibility for undergoing oncogenic tr...

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Bibliographic Details
Main Authors: Guo-Hu Di, Yang Liu, Ying Lu, Jin Liu, Chutse Wu, Hai-Feng Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4242635?pdf=render