Development and validation of a method for the determination of valproic acid in pharmaceutical formulations by high performance liquid chromatography with diode array detection (HPLC-DAD) / Desenvolvimento e validação de um método para a determinação de ácido valpróico em formulações farmacêuticas por cromatografia líquida de alta eficiência acoplada com detector de conjunto de fotodiodos
Valproic acid (VA) is used as an anticonvulsant and is used in the treatment of bipolar disorder and depression. The offi cial analytical method for this drug in the compendia is gas chromatography, which is unavailable in many quality control laboratories. Here, we report a validated alternative met...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2013-02-01
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| Series: | Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia |
| Subjects: | |
| Online Access: | http://www.visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/16/14 |