Early Imaging Biomarker of Myocardial Glucose Adaptations in High-Fat-Diet-Induced Insulin Resistance Model by Using 18F-FDG PET and [U-13C]glucose Nuclear Magnetic Resonance Tracer

Background. High-fat diet (HFD) induces systemic insulin resistance leading to myocardial dysfunction. We aim to characterize the early adaptations of myocardial glucose utility to HFD-induced insulin resistance. Methods. Male Sprague–Dawley rats were assigned into two groups, fed a regular chow die...

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Bibliographic Details
Main Authors: Yi-Hsiu Chung, Kuan-Ying Lu, Shao-Chieh Chiu, Chi-Jen Lo, Li-Man Hung, Jiung-Pang Huang, Mei-Ling Cheng, Chao-Hung Wang, Cheng-Kun Tsai, Yu-Chun Lin, Shang-Hung Chang, Gigin Lin
Format: Article
Language:English
Published: Hindawi-Wiley 2018-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2018/8751267