The Role of CX3CL1 and ADAM17 in Pathogenesis of Diffuse Parenchymal Lung Diseases

Fractalkine (CX3CL1) is a unique chemokine that functions as a chemoattractant for effector cytotoxic lymphocytes and macrophages expressing fractalkine receptor CX3CR1. CX3CL1 exists in two forms—a soluble and a membrane-bound form. The soluble CX3CL1 is released from cell membranes by proteolysis...

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Bibliographic Details
Main Authors: Jan Urban, Magda Suchankova, Martina Ganovska, Vladimir Leksa, Frantisek Sandor, Eva Tedlova, Brian Konig, Maria Bucova
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/6/1074