GLUT10—Lacking in Arterial Tortuosity Syndrome—Is Localized to the Endoplasmic Reticulum of Human Fibroblasts

GLUT10—Lacking in Arterial Tortuosity Syndrome—Is Localized to the Endoplasmic Reticulum of Human Fibroblasts

GLUT10 belongs to a family of transporters that catalyze the uptake of sugars/polyols by facilitated diffusion. Loss-of-function mutations in the SLC2A10 gene encoding GLUT10 are responsible for arterial tortuosity syndrome (ATS). Since subcellular distribution of the transporter is dubious, we aime...

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Bibliographic Details
Main Authors: Alessandra Gamberucci, Paola Marcolongo, Csilla E. Németh, Nicoletta Zoppi, András Szarka, Nicola Chiarelli, Tamás Hegedűs, Marco Ritelli, Giulia Carini, Andy Willaert, Bert L. Callewaert, Paul J. Coucke, Angiolo Benedetti, Éva Margittai, Rosella Fulceri, Gábor Bánhegyi, Marina Colombi
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
GLUT10
arterial tortuosity syndrome
dehydroascorbic acid
endoplasmic reticulum
nuclear envelope
Fe2+/2-oxoglutarate dependent dehydrogenases
Online Access:https://www.mdpi.com/1422-0067/18/8/1820

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https://www.mdpi.com/1422-0067/18/8/1820

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