A synergetic screening approach with companion effector for combination therapy: application to retinoblastoma.

For many cancers, the lack of potency and the toxicity of current drugs limits the dose achievable in patients and the efficacy of treatment. Among them, retinoblastoma is a rare cancer of the eye for which better chemotherapeutic options are needed. Combination therapy is a compelling approach to e...

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Bibliographic Details
Main Authors: Jeni P Mahida, Christophe Antczak, Daniel Decarlo, Kathryn G Champ, Jasmine H Francis, Brian Marr, Arthur S Polans, Daniel M Albert, David H Abramson, Hakim Djaballah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3602587?pdf=render