CELL CYCLE REGULATING GENES AND THEIR PROTEIN EXPRESSION IN SQUAMOUS CELL CARCINOMA OF THE LARYNX AND HYPOPHARYNX

<p>Background. The major mechanisms involved in genomic instability during tumour progression are loss of heterozygosity (LOH) and microsatellite instability (MSI). The most frequently affected are the tumor suppressor genes (TSG). Alterations of cell cycle proteins contribute to the developme...

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Bibliographic Details
Main Authors: Metka Volavšek, Damjan Glavač, Nina Gale
Format: Article
Language:English
Published: Slovenian Medical Association 2002-12-01
Series:Zdravniški Vestnik
Subjects:
p53
p21
p16
Rb
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/1761