Master Regulators of Signaling Pathways: An Application to the Analysis of Gene Regulation in Breast Cancer

Analysis of gene regulatory networks allows the identification of master transcriptional factors that control specific groups of genes. In this work, we inferred a gene regulatory network from a large dataset of breast cancer samples to identify the master transcriptional factors that control the ge...

Full description

Bibliographic Details
Main Authors: Diana Tapia-Carrillo, Hugo Tovar, Tadeo Enrique Velazquez-Caldelas, Enrique Hernandez-Lemus
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01180/full