Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release

Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release

Extracellular vesicles (EVs) are identified as mediators of intercellular communication and cellular regulation. In the immune system, EVs play a role in antigen presentation as a part of cellular communication. To enable drug discovery and characterization of compounds that affect EV biogenesis, fu...

Full description

Bibliographic Details
Main Authors: Jonathan Shpigelman, Fitzgerald S. Lao, Shiyin Yao, Chenyang Li, Tetsuya Saito, Fumi Sato-Kaneko, John P. Nolan, Nikunj M. Shukla, Minya Pu, Karen Messer, Howard B. Cottam, Dennis A. Carson, Maripat Corr, Tomoko Hayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
extracellular vesicle
exosome
THP-1
CD63
CD9
luciferase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.668609/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.668609/full

Similar Items