Synaptic GluN2B/CaMKIIα signalling induces synapto-nuclear transport of ERK and Jacob

A central pathway in synaptic plasticity couples N-Methyl-D-Aspartate-receptor (NMDAR)-signalling to the activation of extracellular signal-regulated kinases (ERKs) cascade. ERK-dependency has been demonstrated for several forms of synaptic plasticity as well as learning and memory and includes loca...

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Bibliographic Details
Main Authors: Michelle Melgarejo da Rosa, PingAn Yuanxiang, Riccardo Brambilla, Michael R. Kreutz, Anna Karpova
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00066/full