Synaptic GluN2B/CaMKIIα signalling induces synapto-nuclear transport of ERK and Jacob
A central pathway in synaptic plasticity couples N-Methyl-D-Aspartate-receptor (NMDAR)-signalling to the activation of extracellular signal-regulated kinases (ERKs) cascade. ERK-dependency has been demonstrated for several forms of synaptic plasticity as well as learning and memory and includes loca...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-08-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00066/full |