Trapa bispinosa Roxb. extract lowers advanced glycation end-products and increases live births in older patients with assisted reproductive technology: a randomized controlled trial

Abstract Background Advanced glycation end-products (AGE), which accumulate with insulin resistance and aging, impair folliculogenesis and may decrease endometrial receptivity. Hishi (Trapa bispinosa Roxb.) extract, a safe herbal medicine, strongly inhibits AGE formation in vitro. We determined whet...

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Bibliographic Details
Main Authors: Masao Jinno, Ryoji Nagai, Masayoshi Takeuchi, Aiko Watanabe, Koji Teruya, Hikari Sugawa, Naohisa Hatakeyama, Yuichi Jinno
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-021-00832-y