Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade

Radiotherapy (RT) is a conventional method for clinical treatment of local tumors,which can induce tumor-specific immune response and cause the shrinkage of primary tumor and distal metastases via mediating tumor infiltration of CD8+ T cells. Ionizing radiation (IR) induced tumor regression outside...

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Bibliographic Details
Main Authors: Xinrui Zhao, Chunlin Shao
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/10/2762