Down-regulation of miR-200b-targeting Slug axis by cyclosporine A in human gingival fibroblasts

Background/Purpose: Cyclosporine A (CsA) has been used as an immunosuppressive agent with a side effect of gingival overgrowth. It has been known that CsA-induced epithelial-mesenchymal transition (EMT) in gingiva, but the molecular mechanism has not been fully unveiled. The purpose of the study is...

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Bibliographic Details
Main Authors: Taichen Lin, Cheng-Chia Yu, Pei-Ling Hsieh, Yi-Wen Liao, Chuan-Hang Yu, Chun-Jung Chen
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Journal of the Formosan Medical Association
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664618304893