Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Abstract This study explores potential associations between the methylation of promoter-associated CpG sites of the toll-like receptor (TLR)-family, plasma levels of pro-inflammatory proteins and depressive symptoms in young female psychiatric patients. Ratings of depressive symptoms and blood sampl...

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Bibliographic Details
Main Authors: Annica J. Rasmusson, Maike Gallwitz, Bardia Soltanabadi, Diana M. Ciuculete, Jonas Mengel-From, Kaare Christensen, Marianne Nygaard, Mette Soerensen, Adrian E. Boström, Robert Fredriksson, Eva Freyhult, Jessica Mwinyi, Darina Czamara, Elisabeth B. Binder, Helgi B. Schiöth, Janet L. Cunningham
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01481-w