Intrasubtype reassortments cause adaptive amino acid replacements in H3N2 influenza genes.

Reassortments and point mutations are two major contributors to diversity of Influenza A virus; however, the link between these two processes is unclear. It has been suggested that reassortments provoke a temporary increase in the rate of amino acid changes as the viral proteins adapt to new genetic...

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Bibliographic Details
Main Authors: Alexey D Neverov, Ksenia V Lezhnina, Alexey S Kondrashov, Georgii A Bazykin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3886890?pdf=render