Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells

Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells

<i>Background.</i> The design of tendon biomimetic electrospun fleece with Amniotic Epithelial Stem Cells (AECs) that have shown a high tenogenic attitude may represent an alternative strategy to overcome the unsatisfactory results of conventional treatments in tendon regeneration. <i...

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Bibliographic Details
Main Authors: Valentina Russo, Mohammad El Khatib, Lisa di Marcantonio, Massimo Ancora, Ralf Wyrwa, Annunziata Mauro, Torsten Walter, Jürgen Weisser, Maria Rita Citeroni, Francesco Lazzaro, Marta Di Federico, Paolo Berardinelli, Cesare Cammà, Matthias Schnabelrauch, Barbara Barboni
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
aligned fibers
amniotic epithelial stem cells
biomimetic scaffold
electrospinning
epithelial-mesenchymal transition
plga
tendon tissue engineering
tenogenic differentiation
Online Access:https://www.mdpi.com/2073-4409/9/2/303

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https://www.mdpi.com/2073-4409/9/2/303

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