Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers

Epigenetic modifications such as histone modification play an important role in tumorigenesis. There are several evidence that histone deacetylases (HDACs) play a key role in cancer induction and progression by histone deacetylation. Besides, histone acetylation is being accessed as a therapeutic ta...

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Bibliographic Details
Main Authors: Masumeh Sanaei, Fraidoon Kavoosi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2019;volume=8;issue=1;spage=63;epage=63;aulast=Sanaei