Predicting Ovarian/Breast Cancer Pathogenic Risks of Human BRCA1 Gene Variants of Unknown Significance

High-throughput sequencing is gaining popularity in clinical diagnoses, but more and more novel gene variants with unknown clinical significance are being found, giving difficulties to interpretations of people’s genetic data, precise disease diagnoses, and the making of therapeutic strategies and d...

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Bibliographic Details
Main Authors: Hui-Heng Lin, Hongyan Xu, Hongbo Hu, Zhanzhong Ma, Jie Zhou, Qingyun Liang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/6667201