RGD-mediated adhesive interactions are important for peripheral axon outgrowth in vivo

RGD-mediated adhesive interactions are important for peripheral axon outgrowth in vivo

We identify an essential role for the RGD (Arg-Gly-Asp tripeptide) moiety in vivo during adult peripheral neuron regenerative growth. Beyond a peripheral nerve transection there were rises in the fibronectin extracellular matrix, and striking rises in the mRNA and protein expression of integrin subu...

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Bibliographic Details
Main Authors: W.-Q. Liu, J.A. Martinez, J. Durand, W. Wildering, D.W. Zochodne
Format: Article
Language:English
Published: Elsevier 2009-04-01
Series:Neurobiology of Disease
Subjects:
Peripheral nerve regeneration
Integrins
Fibronectin
RGD
Peripheral nerve injury
Axon outgrowth
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002842

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http://www.sciencedirect.com/science/article/pii/S0969996108002842

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