A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast

Transcription of lncRNAs is known to regulate local gene expression. Here the authors describe how orchestrated transcription of two contiguous lncRNAs facilitates a regulatory circuit by which the master regulator for entry into meiosis, IME1, directs the decision to enter meiosis in yeast.

Bibliographic Details
Main Authors: Fabien Moretto, N. Ezgi Wood, Gavin Kelly, Andreas Doncic, Folkert J. van Werven
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03213-z